Anxiety & Depression 5-HTTLPR Test
$149.00
Do you possess a familial history of depression? You may have the “grouchy” gene, which is associated with changes in serotonin levels and an elevated likelihood of experiencing anxiety and depression. You can confirm whether you have this gene by taking a DNA test.
- Identifies the 5-HTTLPR variant of the SLC64A gene
- Individuals carrying the “grouchy” gene have an amplified risk of experiencing feelings of sadness, depression, and anxiety.
- The “grouchy” gene may reduce an individual’s response to antidepressant medications.
- Collection method: Buccal swabs
- Private and confidential online results
Description
Serotonin is a neurotransmitter in the brain responsible for inducing feelings of pleasure and well-being. It is released from neurons, which then signal the brain to experience happiness and contentment.
However, individuals with the “grouchy” gene tend to produce lower levels of the serotonin transporter, resulting in smaller amygdala and cingulate regions in the brain, both of which are involved in emotional responses. This can lead to an increased likelihood of experiencing anxiety and depression. Additionally, such individuals may not respond as effectively to commonly used SSRI antidepressants.
By undergoing a simple mouth swab test, one can determine if they possess the “grouchy” gene.
Description
Serotonin is a neurotransmitter in the brain responsible for inducing feelings of pleasure and well-being. It is released from neurons, which then signal the brain to experience happiness and contentment.
However, individuals with the “grouchy” gene tend to produce lower levels of the serotonin transporter, resulting in smaller amygdala and cingulate regions in the brain, both of which are involved in emotional responses. This can lead to an increased likelihood of experiencing anxiety and depression. Additionally, such individuals may not respond as effectively to commonly used SSRI antidepressants.
By undergoing a simple mouth swab test, one can determine if they possess the “grouchy” gene.
Our testing laboratory is AABB Accredited, ISO/IEC 17025 Certified and participates in the CAP proficiency testing program.
Technical Info
This test identifies the length of the 5-HTTLPR region within the SLC64A gene, enabling the differentiation of the short (S) or “grouchy” form from the long (L) form of the gene. The SLC6A4 gene, located on chromosome 17, is inherited from both parents, resulting in two copies of the gene. Inheriting one or two copies of the short form is associated with an increased risk of depression.
Individuals with two copies of the short, “grouchy” form of the SLC6A4 gene have a higher likelihood of being unhappy, and they will pass this form of the gene to all their children. Conversely, individuals with two copies of the long form have a decreased risk of unhappiness and depression. Heterozygotes possess one copy of the long form and one copy of the short form, which still impacts their level of happiness. These individuals have a 50% chance of passing the “grouchy” gene to their offspring.
